$0 Co-Pay - 12 Months of therapy, renewable annually

Frequently Asked Questions

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Look below for answers to questions you may have about Trokendi XR®

What is Trokendi XR?

Trokendi XR is a prescription medicine used:

  • to prevent migraine headaches in adults and adolescents 12 years and older. Trokendi XR is not used to stop a migraine headache after it starts.
  • to treat certain types of seizures (partial onset seizures and primary generalized tonic-clonic seizures) in people 6 years and older
  • with other medicines to treat certain types of seizures (partial onset seizures, primary generalized tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome) in adults and children 6 years and older

What should I tell my doctor before taking Trokendi XR?

Before taking Trokendi XR, tell your doctor about all your medical conditions, including if you:

  • have or have had depression, mood problems, or suicidal thoughts or behavior
  • have kidney problems, kidney stones, or are getting kidney dialysis
  • have a history of metabolic acidosis (too much acid in the blood)
  • have liver problems
  • have weak, brittle, or soft bones (osteomalacia, osteoporosis, osteopenia, or decreased bone density)
  • have lung or breathing problems
  • have eye problems, especially glaucoma
  • have diarrhea
  • have a growth problem
  • are on a diet high in fat and low in carbohydrates, which is called a ketogenic diet
  • are having surgery
  • are pregnant or plan to become pregnant
  • are breastfeeding. Trokendi XR passes into your breast milk. It is not known if the Trokendi XR that passes into breast milk can harm your baby. Talk to your doctor about the best way to feed your baby if you take Trokendi XR

Should I tell my doctor about other medicines I take?

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Trokendi XR and other medicines may affect each other, causing side effects. Especially, tell your doctor if you take:

  • metformin (such as Glucophage)
  • valproic acid (such as DEPAKENE® or DEPAKOTE®)
  • any medicines that impair or decrease your thinking, concentration, or muscle coordination
  • birth control pills. Trokendi XR may make your birth control pills less effective. Tell your doctor if your menstrual bleeding changes while you are taking birth control pills and Trokendi XR

How should I take Trokendi XR?

  • Take Trokendi XR capsules whole. Do not sprinkle Trokendi XR on food, or break, crush, dissolve, or chew Trokendi XR capsules before swallowing
  • If you cannot swallow Trokendi XR capsules whole, tell your doctor. You may need a different medicine

Can I change my dose or stop taking Trokendi XR?

  • Take Trokendi XR exactly as prescribed
  • Your doctor may change your dose. Do not change your dose without talking to your doctor
  • Do not stop taking Trokendi XR without talking to your doctor. Stopping Trokendi XR suddenly may cause serious problems. If you have epilepsy and you stop taking Trokendi XR suddenly, you may have seizures that do not stop. Your doctor will tell you how to stop taking Trokendi XR slowly

What happens if I miss a dose?

If you miss a single dose of Trokendi XR, take it as soon as you can. Do not double your dose. If you have missed more than one dose, you should call your doctor for advice.

What should I avoid while taking Trokendi XR?

  • Do not drink alcohol within 6 hours prior to and 6 hours after Trokendi XR administration
  • Do not drive a car or operate heavy machinery until you know how Trokendi XR affects you. Trokendi XR can slow your thinking and motor skills, and may affect vision

Can I take Trokendi XR during pregnancy?

Trokendi XR can harm your unborn baby.

  • If you take Trokendi XR during pregnancy, your baby has a higher risk for birth defects called cleft lip and cleft palate. These defects can begin early in pregnancy, even before you know you are pregnant
  • Cleft lip and cleft palate may happen even in children born to women who are not taking any medicines and do not have other risk factors
  • Also, if you take Trokendi XR during pregnancy, your baby may be smaller than expected at birth. The long-term effects of this are not known.
  • There may be other medicines to treat your condition that have a lower chance of birth defects
  • All women of childbearing age should talk to their doctors about using other possible treatments instead of Trokendi XR. If the decision is made to use Trokendi XR, you should use effective birth control (contraception) unless you are planning to become pregnant. You should talk to your doctor about the best kind of birth control to use while you are taking Trokendi XR

What if I become pregnant while taking Trokendi XR?

  • Tell your doctor right away if you become pregnant while taking Trokendi XR. You and your doctor should decide if you will continue to take Trokendi XR while you are pregnant
  • Metabolic acidosis may have harmful effects on your baby. Talk to your doctor if Trokendi XR has caused metabolic acidosis during your pregnancy
  • Also, if you take Trokendi XR during pregnancy, your baby may be smaller than expected at birth. Talk to your doctor if you have questions about this risk during pregnancy.
  • Pregnancy Registry: If you become pregnant while taking Trokendi XR, talk to your doctor about registering with the North American Antiepileptic Drug Pregnancy Registry. You can enroll in this registry by calling 1-888-233-2334. The purpose of this registry is to collect information about the safety of Trokendi XR and other antiepileptic drugs during pregnancy

What are the possible side effects of Trokendi XR?

Trokendi XR may cause serious side effects, including:

  • High blood ammonia levels. High ammonia in the blood can affect your mental activities, slow your alertness, make you feel tired, or cause vomiting. This has happened when Trokendi XR is taken with a medicine called valproic acid (DEPAKENE and DEPAKOTE)
  • Kidney stones. Drink plenty of fluids when taking Trokendi XR to decrease your chances of getting kidney stones
  • Low body temperature. Taking Trokendi XR when you are also taking valproic acid may cause a drop in body temperature to less than 95ºF, feeling tired, confusion, or coma
  • Effects on thinking and alertness. Trokendi XR may affect how you think, and may cause confusion, problems with concentration, attention, memory, or speech. Trokendi XR may cause depression or mood problems, tiredness, and sleepiness
  • Dizziness or loss of muscle coordination

These are not all the possible side effects of Trokendi XR. Please see the Patient Medication Guide or talk to your doctor for more information about possible side effects of Trokendi XR.

When should I contact my doctor?

Call a doctor right away if you have any of these symptoms, especially if they are new, worse, or worry you:

  • thoughts about suicide or dying
  • attempts to commit suicide
  • new or worse depression
  • new or worse anxiety
  • feeling agitated or restless
  • panic attacks
  • trouble sleeping (insomnia)
  • new or worse irritability
  • acting aggressive, being angry or violent
  • acting on dangerous impulses
  • an extreme increase in activity and talking (mania)
  • other unusual changes in behavior or mood

What are the possible early symptoms of suicidal thoughts and actions?

  • Pay attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings
  • Keep all follow-up visits with your doctor as scheduled
  • Call your doctor between visits as needed, especially if you are worried about symptoms

How should I store Trokendi XR?

  • Store Trokendi XR capsules at room temperature between 59°F to 86°F (15°C to 30°C)
  • Keep Trokendi XR in a tightly closed container
  • Keep Trokendi XR dry and away from moisture and light
  • Keep Trokendi XR and all medicines out of the reach of children